The Modulation Of Fertility Hormones Stress In Female Rats Initiated By Toxicants In Diet Prepared With Fish Smoked With Polyethylene (Plastic) Materials As Fuel Source:- Okafor Chinemerem C

ABSTRACT x This study investigated the modulation offertility hormones stress in female rats initiated by toxicants in diet prepared with fish smoked with polyethylene (plastic) materials as fuel source. The clove seed was air dried and blended into powder form using a mechanical blender. The fishes were grouped into two, one group was smoked with firewood, while the other group was smoked with polyethylene materials as fuel sources for a period of five days. The female wistar rats were grouped into seven groups, one control group and six experimental groups. Group one: (100% pellets), Group two: (60% pellets and 40% fish smoked with firewood), Group three: (50% pellets, 40% fish smoked with firewood and 19% clove), (Group four: 50% pellets, 40% fish smoked with firewood, 5% clove, and 5% vitamin E supplement), Group five: (60% pellets and 40% fish smoked with polyethylene materials), Group six: (50% pellets, 40% fish smoked with polyethylene materials, 10% clove), and Group seven: (50% pellets, 40% fish smoked with polyethylene materials, 5% clove, 5% vitamin E supplement). The feeding was done for a period of 30 days. The results of progesterone showed a significant (p<0.05) decrease in progesterone levels in group BP, CF and DP compared to the normal control group. There was non significant (p<0.05) difference in group CP compared to group DP. LH level showed a significant (p<0.05) decrease in the LH level in CP, DP compared to the DF group. Group BF and CF showed a non significant (p<0.05) difference compared DP group. There was non significant (p<0.05) difference in the FSH level in BF compared to the DP group. Group BP, CF and CP showed a significant (p<0.05) increase compared XX control group. There was a significant (P<0.05) increase in prolactin level in BP and CP groups compared to the DP and normal control group. There was also a non significant (P<0.05) difference in BP compared to the CF group. It can be concluded that roasting of fish, especially using polyethylene materials, generates a lot of toxicants. Clove seeds might also provide a protective effect on female reproductive system and low levels ofthe extract could increase steroidal hormones.