The Effect Of Methanol Extract Of Colocasia Esculenta On Lipid Profile Parameter Of Dihydrotestosterone/Estradiol-Valerate Induced Benign Prostate Hyperplasia In Male Albino Rat:- Okposi Kokomma L
ABSTRACT
Colocasia
esculenta is a medicinal plant believed to have many agent acting in many ways
for the health benefit of human. The study investigated the acute toxivity,
phytochemicalcontent and effect of methanol extract on lipid profile parameters
and biomarkers of prostate dysfunction. The result indicated the high level of
oxalate (28.15). Other phytochemical constituent such as
flavonoid,phenols,phytate and reducing sugar are found in moderate amount. The
result of LD-, was 5000mg/kgbody weight. There was no significant difference
(p>0.05) in the relative heart, kidney and lungs weight. The relative
prostate weight increased significantly (p<0.05) in disease control relative
to other groups. The result shows a significant (p<0.05) reduction in the
prostatic specific antigen (PSA) in the treatment groups when compared with the
disease control group. The result of the lipid profile parameters showed that
cholesterol, TAG, LDL and VLDL increased significantly (p<0.05) in disease
control relative to other experimental groups while HDL-cholesterol increased
(p<0.05) significantly in finasteride and extract treated groups relative to
the disease control group. This study suggests that there is strong indication
of the hypolipidemic activity of methanol extract of colocasia esculenta. It
also showed that it can be used in the management of BPH. Therefore the result
showed that colocasia esculenta corm can serve as a source of useful drugs
because of the presence of phytochemical agent.
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MICHAEL, U (2024). The Effect Of Methanol Extract Of Colocasia Esculenta On Lipid Profile Parameter Of Dihydrotestosterone/Estradiol-Valerate Induced Benign Prostate Hyperplasia In Male Albino Rat:- Okposi Kokomma L. Mouau.afribary.org: Retrieved Dec 22, 2024, from https://repository.mouau.edu.ng/work/view/the-effect-of-methanol-extract-of-colocasia-esculenta-on-lipid-profile-parameter-of-dihydrotestosteroneestradiol-valerate-induced-benign-prostate-hyperplasia-in-male-albino-rat-okposi-kokomma-l-7-2
UNIVERSITY, MICHAEL. "The Effect Of Methanol Extract Of Colocasia Esculenta On Lipid Profile Parameter Of Dihydrotestosterone/Estradiol-Valerate Induced Benign Prostate Hyperplasia In Male Albino Rat:- Okposi Kokomma L" Mouau.afribary.org. Mouau.afribary.org, 09 Dec. 2024, https://repository.mouau.edu.ng/work/view/the-effect-of-methanol-extract-of-colocasia-esculenta-on-lipid-profile-parameter-of-dihydrotestosteroneestradiol-valerate-induced-benign-prostate-hyperplasia-in-male-albino-rat-okposi-kokomma-l-7-2. Accessed 22 Dec. 2024.
UNIVERSITY, MICHAEL. "The Effect Of Methanol Extract Of Colocasia Esculenta On Lipid Profile Parameter Of Dihydrotestosterone/Estradiol-Valerate Induced Benign Prostate Hyperplasia In Male Albino Rat:- Okposi Kokomma L". Mouau.afribary.org, Mouau.afribary.org, 09 Dec. 2024. Web. 22 Dec. 2024. < https://repository.mouau.edu.ng/work/view/the-effect-of-methanol-extract-of-colocasia-esculenta-on-lipid-profile-parameter-of-dihydrotestosteroneestradiol-valerate-induced-benign-prostate-hyperplasia-in-male-albino-rat-okposi-kokomma-l-7-2 >.
UNIVERSITY, MICHAEL. "The Effect Of Methanol Extract Of Colocasia Esculenta On Lipid Profile Parameter Of Dihydrotestosterone/Estradiol-Valerate Induced Benign Prostate Hyperplasia In Male Albino Rat:- Okposi Kokomma L" Mouau.afribary.org (2024). Accessed 22 Dec. 2024. https://repository.mouau.edu.ng/work/view/the-effect-of-methanol-extract-of-colocasia-esculenta-on-lipid-profile-parameter-of-dihydrotestosteroneestradiol-valerate-induced-benign-prostate-hyperplasia-in-male-albino-rat-okposi-kokomma-l-7-2