Protective Effect 0f Annona Muricata Linn Aqueous Leaf Extract On Liver Enzymes Of Male Wistar Rats Treated With Used Motor Engine Oil:- Udochukwu Amarachi D

Michael Okpara University | 62 pages (10793 words) | Projects
Biochemistry | Co Authors: UDOCHUKWU AMARACHI DEBORAH

ABSTRACT

The liver is a vital organ in the body with a wide range of metabolic functions. It is very important for survival and cannot be compensated for in the absence of long term liver function. The liver which plays a crucial role in metabolism also metabolizes heavy metals and when exposed to chemicals which may probably beheavy metals lauded in used motor engine oil can lead to liver dysfunction, cell damage and organ failure. An elevation ofliver enzymes like ALT, ASP and ALP could suggest a liver malfunction. This study was aimed at evaluating the protective effect ofAnnona Muricata (linn) aqueous leaf extract on AST, ALP and ASP of male Wistar rats treated with used motor engine oil. Thirty-five male Wistar rats were randomly distributed into 7 groups of five rats each. Group A received standard diets, group B received UMEO only, group C and D received lOOmg/kg and 200mg/kg ofAnnona muricata leaf extract respectively for two weeks before been treated with UMEO for the remaining two weeks, group E and F received lOOmg/kg and 200mg/kg respectively of Annona muricata after been treated with UMEO for the first two weeks while Group G received the standard drug Vitamin C after receiving UMEO. The experiment lasted for a period of 28 days. There were significant (p<0.05) increase in ALT, AST and ALP levels in animals treated with UMEO but similarly a significant decrease in AST, ALP and ASP levels was observed with administration ofthe leaf extract. This study showed that UMEO is capable of inducing hepatoxicity and Annona Muricata leaf extract possess hepato-protective ability as increase in liver enzymes were observed. Lienee, Annona moricata leaf extract may serve in liver treatment therapies

 

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APA

MICHAEL, U (2024). Protective Effect 0f Annona Muricata Linn Aqueous Leaf Extract On Liver Enzymes Of Male Wistar Rats Treated With Used Motor Engine Oil:- Udochukwu Amarachi D. Mouau.afribary.org: Retrieved Nov 16, 2024, from https://repository.mouau.edu.ng/work/view/protective-effect-0f-annona-muricata-linn-aqueous-leaf-extract-on-liver-enzymes-of-male-wistar-rats-treated-with-used-motor-engine-oil-udochukwu-amarachi-d-7-2

MLA 8th

UNIVERSITY, MICHAEL. "Protective Effect 0f Annona Muricata Linn Aqueous Leaf Extract On Liver Enzymes Of Male Wistar Rats Treated With Used Motor Engine Oil:- Udochukwu Amarachi D" Mouau.afribary.org. Mouau.afribary.org, 10 Oct. 2024, https://repository.mouau.edu.ng/work/view/protective-effect-0f-annona-muricata-linn-aqueous-leaf-extract-on-liver-enzymes-of-male-wistar-rats-treated-with-used-motor-engine-oil-udochukwu-amarachi-d-7-2. Accessed 16 Nov. 2024.

MLA7

UNIVERSITY, MICHAEL. "Protective Effect 0f Annona Muricata Linn Aqueous Leaf Extract On Liver Enzymes Of Male Wistar Rats Treated With Used Motor Engine Oil:- Udochukwu Amarachi D". Mouau.afribary.org, Mouau.afribary.org, 10 Oct. 2024. Web. 16 Nov. 2024. < https://repository.mouau.edu.ng/work/view/protective-effect-0f-annona-muricata-linn-aqueous-leaf-extract-on-liver-enzymes-of-male-wistar-rats-treated-with-used-motor-engine-oil-udochukwu-amarachi-d-7-2 >.

Chicago

UNIVERSITY, MICHAEL. "Protective Effect 0f Annona Muricata Linn Aqueous Leaf Extract On Liver Enzymes Of Male Wistar Rats Treated With Used Motor Engine Oil:- Udochukwu Amarachi D" Mouau.afribary.org (2024). Accessed 16 Nov. 2024. https://repository.mouau.edu.ng/work/view/protective-effect-0f-annona-muricata-linn-aqueous-leaf-extract-on-liver-enzymes-of-male-wistar-rats-treated-with-used-motor-engine-oil-udochukwu-amarachi-d-7-2

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