The Effect Of Cassava Cyanide On The Antioxidant (Glutathione) And Some Clinically Important Enzymes Of Rats.
ABSTRACT
The effect of cassava cyanide on the
antioxidant (glutathione) status and some clinically important enzymes were
investigated chemically and enzymatica in male albino wister rats fed for 28days with
high cassava diet containing 54.6mg CN- (100%) DM and 10% protein supplement.
Urinary and serum cyanide and thiocyanate analysis was carried out. The mean
serum cyanide and thiocyanale levels where 6. '73mg/I and 2.92mg/I after 7 days
and 1.96mg/I and 1.5 mg/I after 28 days respectively. The mean urinary cyanide
and thiocyanate levels were 5.69 mg/I and 10.81mg/I after 28 days respectively.
The mean blood glutathionc levels were 0.150, 0.373, 0.03, and 0.024 after 7,
14, 21 and 28 days respectively showing depletion in blood glutathione with
increase in cassava cyanide intake. There was mean increase in plasma activity
of aspartate amino transferees (AST) alanine amino transferees (ALT) and
alkaline phosphatase (ALP) by 91.25%, 100% and 137 % respectively above that of
control. There was elevation in blood glucose iii the test animals while time
level of protein and albumin remain within the normal range for both the test
and control animals.
0.0
ANYANWU, O (2021). The Effect Of Cassava Cyanide On The Antioxidant (Glutathione) And Some Clinically Important Enzymes Of Rats. . Mouau.afribary.org: Retrieved Nov 17, 2024, from https://repository.mouau.edu.ng/work/view/the-effect-of-cassava-cyanide-on-the-antioxidant-glutathione-and-some-clinically-important-enzymes-of-rats-7-2
O, ANYANWU. "The Effect Of Cassava Cyanide On The Antioxidant (Glutathione) And Some Clinically Important Enzymes Of Rats. " Mouau.afribary.org. Mouau.afribary.org, 01 Jul. 2021, https://repository.mouau.edu.ng/work/view/the-effect-of-cassava-cyanide-on-the-antioxidant-glutathione-and-some-clinically-important-enzymes-of-rats-7-2. Accessed 17 Nov. 2024.
O, ANYANWU. "The Effect Of Cassava Cyanide On The Antioxidant (Glutathione) And Some Clinically Important Enzymes Of Rats. ". Mouau.afribary.org, Mouau.afribary.org, 01 Jul. 2021. Web. 17 Nov. 2024. < https://repository.mouau.edu.ng/work/view/the-effect-of-cassava-cyanide-on-the-antioxidant-glutathione-and-some-clinically-important-enzymes-of-rats-7-2 >.
O, ANYANWU. "The Effect Of Cassava Cyanide On The Antioxidant (Glutathione) And Some Clinically Important Enzymes Of Rats. " Mouau.afribary.org (2021). Accessed 17 Nov. 2024. https://repository.mouau.edu.ng/work/view/the-effect-of-cassava-cyanide-on-the-antioxidant-glutathione-and-some-clinically-important-enzymes-of-rats-7-2