The Effect of Aqueous Extract of Pleurotus ostreatus grown on HCl-treated Palm Oil Bunch on some hematological parameters in Wistar Albino Rats
ABSTRACT
This
study investigated the effect of aqueous extract ofPleurotus ostreatus grown on
HCl-treated Palm Oil Bunch on some hematological parameters (WBC, RBC, PCV Hb
and Platelet) in Wistar Albino Rats. Twenty-four rats weighing 80- 130g were
divided into six groups of four rats per group. Group 1 was control group.
Group 2, 3, 4, 5 and 6 were treated with the plant extracts at 0.1%, 0.2%,
0.3%, 0.4% and 0.5% HC1 concentrations respectively. Oral administration of
aqueous extract ofPleurotus ostreatus lasted for 21 days. At the end ofthe 21
days, blood samples were collected by ocular puncture for the determination of
hematological parameter: WBC, Hb, PCV RBC and platelets after which the rats
were sacrificed. The results showed a significant (P<0.05) increase in the
WBC in two test groups (0.2% HC1 and 0.3% HC1) when compared against the
control. There was no significant (P>0.05) difference in the level of HB,
RBC, PCV and Platelets in five extract groups (0.1 % HC1, 0.2 % HC1, 0.3% HC1,
0.4 % HC1 and 0.5% HC1) when compared against the control. The results suggest
that the aqueous extract ofPleurotus ostreatus grown on HCl-treated Palm Oil
Bunch has no toxicological effect on the hematological parameters (PCV, Hb,
RBC, and Platelets) and therefore is good for consumption. On the other hand,
the . significant increase in the WBC level shows that the extract has the
capacity to increase the immune system levels in man and animals.
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EDITH, N (2023). The Effect of Aqueous Extract of Pleurotus ostreatus grown on HCl-treated Palm Oil Bunch on some hematological parameters in Wistar Albino Rats. Mouau.afribary.org: Retrieved Nov 17, 2024, from https://repository.mouau.edu.ng/work/view/the-effect-of-aqueous-extract-of-pleurotus-ostreatus-grown-on-hcl-treated-palm-oil-bunch-on-some-hematological-parameters-in-wistar-albino-rats-7-2
NKIRUKA, EDITH. "The Effect of Aqueous Extract of Pleurotus ostreatus grown on HCl-treated Palm Oil Bunch on some hematological parameters in Wistar Albino Rats" Mouau.afribary.org. Mouau.afribary.org, 12 Oct. 2023, https://repository.mouau.edu.ng/work/view/the-effect-of-aqueous-extract-of-pleurotus-ostreatus-grown-on-hcl-treated-palm-oil-bunch-on-some-hematological-parameters-in-wistar-albino-rats-7-2. Accessed 17 Nov. 2024.
NKIRUKA, EDITH. "The Effect of Aqueous Extract of Pleurotus ostreatus grown on HCl-treated Palm Oil Bunch on some hematological parameters in Wistar Albino Rats". Mouau.afribary.org, Mouau.afribary.org, 12 Oct. 2023. Web. 17 Nov. 2024. < https://repository.mouau.edu.ng/work/view/the-effect-of-aqueous-extract-of-pleurotus-ostreatus-grown-on-hcl-treated-palm-oil-bunch-on-some-hematological-parameters-in-wistar-albino-rats-7-2 >.
NKIRUKA, EDITH. "The Effect of Aqueous Extract of Pleurotus ostreatus grown on HCl-treated Palm Oil Bunch on some hematological parameters in Wistar Albino Rats" Mouau.afribary.org (2023). Accessed 17 Nov. 2024. https://repository.mouau.edu.ng/work/view/the-effect-of-aqueous-extract-of-pleurotus-ostreatus-grown-on-hcl-treated-palm-oil-bunch-on-some-hematological-parameters-in-wistar-albino-rats-7-2