ABSTRACT

Urinary tract infection (UTI) is one of the common bacterial infections in man. The changing antimicrobial sensitivity in UTI demands use of appropriate antibiotics. This study was conducted to determine the prevalence and antimicrobial susceptibility of uropathogens. Clean catch midstream urine samples were collected from 200 students of Michael Okpara University Of Agriculture,Umudike. Antimicrobial susceptibility was performed by disc diffusion method. The results revealed that out of 200 urine samples, 127(63.5%) were found positive. The prevalence was higher in females than in males (females: 44.5; males: 19%). Age group of 21-25 years showed higher prevalence of UTI. The most common organisms isolated were Escherichia coli, Klebsiella pneumoniae , Proteus spp and Pseudomonas aeruginosa. These represented 52.76%, 19.69%, 15.75% and 11.81% of isolates respectively. Ofloxacin, Cefexime, Levofloxacin and Ceftriaxone Sulbactarm were found the most susceptible drug against isolated uropathogens. In conclusion, the gram negative organisms isolated showed to be very sensitive to the following drugs; Ofloxacin,Cefexime,Levofloxacin and Ceftriaxone Sulbactarm and it could therefore be suggested that in the situation of clear UTI symptoms and in the absence of physician that these drugs (Ofloxacin ,Cefexime,Levofloxacin and Ceftriaxone Sulbactarm) could be  used.Therefore isolation of pathogens in urine and subsequent antibiotic testing are vital in the treatment of urinary tract infection.