ABSTRACT

The bacterial isolates from various clinical (urine, high vaginal swab, wound swab, pus and stool) and their antibiotics profile were investigated. In this study, a total of seven (7) bacterial species were isolated and identified by their morphological characteristics, pigmentation on media, microscopy, biochemical and sugar fermentation methods. Bacterial species isolated include; Staphylococcus aurues, Escherichia co/i, Shige/la specie, Pseudomonas species, Streptococcus species, Proteus species and Scilrnonel/a species respectively. It was observed in this study that Escherichia co/i and Staphylococcus aurues were the most frequently distributed isolates among the samples with a percentage occurrence of41(34.1%) and 22(18.3%) respectively. It was also revealed in this study that the antibiotic susceptibility and resistant profile for Gram Negative and Positive isolates varied. Escherichia co/i and Staphylococcus aurues isolates showed high level of sensitivity to the antibiotic drugs; Levofloxacin (20mcg), Gentamycin (lOmcg), and Ciprofloxacin (lOmcg). Escherichia co/i, Staphylococcus aureus, Streptococcus spp and Shigel/a spp isolates showed high level resistance against Arnoxill (20mcg), (Chloramphenicol 30mcg), Erythromycin (30rncg), Ampiclox (20mcg), Streptomycin (30mcg), and Rifampicin (20mcg) antibiotics. This study showed that Levofloxacin (20mcg), Gentamycin (lOrncg), and Ciprofloxacin (lomcg) antibiotics had the capacity to kill Escherichia co/i and Staphylococcus aurues. However, Levofloxacin (20rncg), Gentamycin (lOmcg), and Ciprofloxacin (lOmcg) antibiotic could be of alternative of choice to use and to control Gram-Negative and Gram Positive bacterial infection as an effective antibact&rial agent as revealed from the present study.