ABSTRACT

The plant kingdom offers a variety of a wide range of plants with natural antimicrobial and medicinal values. The widespread of diseases of microbial origin remains alarming, particularly of serious concerns in the tropics and sub-tropics. The high costs of newer and effective drugs and other factors have made the choice of traditional herbal medicine considered against these pathogenic microbes, and making it more economical. N. leavis is one of the plants with magical effects, which is commonly called tree of life. N. leavis has been reported to have medicinal value ranging from anti-inflammatory, anti-microbial, anti-fungi, analgesic and wound healing properties.  The results obtained from the phytochemical analysis of N. leavis leave extracts showed the presence of Alkaloids, Phenols, Tannins, Protein etc. The highest yield was obtained from the water extract with protein giving a yield of 2.92. Phytochemical are naturally occurring and are believed to be effective in combating or preventing disease due to their antioxidant properties. While in the course of this study, it was discovered that Alkaloid, Tannins, Ether, Protein, Saponin and Phenol were all positive. While in the antimicrobial effect of N. leavis it was discovered that the highest yield was obtained from the water extract with the zone of inhibition on E.coli was 38mm. It was discovered that N. leavis has a clear zone of inhibition on E.coli and meanwhile there were no zone of inhibition on Methicillin resistant S. aureus in recommendation, I suggest that N. leavis is used to treat and E.coli induced infection.