Evaluation of the In vitro activity of aqueous fraction of phenolic-rich extract of Acalypha wilkesiana Leaves:- Okorie, Nneoma A
ABSTRACT
This
study was carried out to investigate the antioxidant efficacy of at different
concentrations of Acalypha -wilkesiana extract at 20mg/ml, 40 mg/ml, 60 mg/ml,
80 mg/ml and 100 mg/ml using vitamin C as a reference compound. Acalypha
wilkesiana extract was analyzed for its antioxidant efficacy as reducing power
ability as well as its ability to scavenge free radicals such as 1,1-
diphenyl2-picryl hydrazyl, and hydrogen peroxide (H2O2). The results of the
study showed significant and concentration-dependent antioxidant and free
radical scavenging activities. Consequently, the Acalypha -wilkesiana extract
exerted significant scavenging activities of 1,1- diphenyl-2-picryl hydrazyl in
a concentration-dependent manner by 12.973%, 13.632%, 22.22% and 30.17% at
20mg/ml, 40 mg/ml, 60 mg/ml, 80 mg/ml and 100 mg/ml respectively. For the
extracts scavenging activity for hydrogen peroxide free radicals, the results
showed significant scavenging activities. These findings justify the biological
and traditional uses of Acalypha ■wilkesiana or its secondary metabolites as
confirmed by its promising antioxidant efficacy.
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NNEOMA, A (2024). Evaluation of the In vitro activity of aqueous fraction of phenolic-rich extract of Acalypha wilkesiana Leaves:- Okorie, Nneoma A. Mouau.afribary.org: Retrieved Nov 17, 2024, from https://repository.mouau.edu.ng/work/view/evaluation-of-the-in-vitro-activity-of-aqueous-fraction-of-phenolic-rich-extract-of-acalypha-wilkesiana-leaves-okorie-nneoma-a-7-2
ANNABELLE, NNEOMA. "Evaluation of the In vitro activity of aqueous fraction of phenolic-rich extract of Acalypha wilkesiana Leaves:- Okorie, Nneoma A" Mouau.afribary.org. Mouau.afribary.org, 04 Mar. 2024, https://repository.mouau.edu.ng/work/view/evaluation-of-the-in-vitro-activity-of-aqueous-fraction-of-phenolic-rich-extract-of-acalypha-wilkesiana-leaves-okorie-nneoma-a-7-2. Accessed 17 Nov. 2024.
ANNABELLE, NNEOMA. "Evaluation of the In vitro activity of aqueous fraction of phenolic-rich extract of Acalypha wilkesiana Leaves:- Okorie, Nneoma A". Mouau.afribary.org, Mouau.afribary.org, 04 Mar. 2024. Web. 17 Nov. 2024. < https://repository.mouau.edu.ng/work/view/evaluation-of-the-in-vitro-activity-of-aqueous-fraction-of-phenolic-rich-extract-of-acalypha-wilkesiana-leaves-okorie-nneoma-a-7-2 >.
ANNABELLE, NNEOMA. "Evaluation of the In vitro activity of aqueous fraction of phenolic-rich extract of Acalypha wilkesiana Leaves:- Okorie, Nneoma A" Mouau.afribary.org (2024). Accessed 17 Nov. 2024. https://repository.mouau.edu.ng/work/view/evaluation-of-the-in-vitro-activity-of-aqueous-fraction-of-phenolic-rich-extract-of-acalypha-wilkesiana-leaves-okorie-nneoma-a-7-2