Evaluating The Antimicrobial Activity Of Vernonia Amygdalina (Bitter Leaf Extract) On Staphylococcus Aureus, Escherichia Coli And Pseudomonas Aeruginosa
ABSTRACT
Human beings have used plants to treat common infectious disease and some of these traditional practices are still included as part of the habitual treatment of various maladies. Today, researches are focusing on the discovery of new therapeutic substances of natural origin with possible low or no toxicity to humans, animals and the environment based on the ethnomedicinal practices. Antimicrobial activity of the V. amygdalina (Bitter leaf) aqueous and ethanolic extracts against the test isolates, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa were assessed using minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and inhibitory zone diameter(IZD) at the dilutions of 100mg/ml, 50mg/ml, 25mg/ml, 12.5mg/ml 6.25ml/ml and 3.125mg/ml respectively . Both the water and ethanolic extract concentrations of V. amygdalina leaf produced observable in-vitro antibacteria effects on all the organisms at 100mg/ml and 50mg/ml. Ethanolic extract produced better antibacterial effects against the test isolate than that of aqueous extract. This research has shown that V. amygdalina leaves have great antibacterial activities. This can be applied in the treatment of the disease caused by the test organisms.
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IDUME, I (2021). Evaluating The Antimicrobial Activity Of Vernonia Amygdalina (Bitter Leaf Extract) On Staphylococcus Aureus, Escherichia Coli And Pseudomonas Aeruginosa. Mouau.afribary.org: Retrieved Nov 15, 2024, from https://repository.mouau.edu.ng/work/view/evaluating-the-antimicrobial-activity-of-vernonia-amygdalina-bitter-leaf-extract-on-staphylococcus-aureus-escherichia-coli-and-pseudomonas-aeruginosa-7-2
IDUME, IDUME. "Evaluating The Antimicrobial Activity Of Vernonia Amygdalina (Bitter Leaf Extract) On Staphylococcus Aureus, Escherichia Coli And Pseudomonas Aeruginosa" Mouau.afribary.org. Mouau.afribary.org, 04 Nov. 2021, https://repository.mouau.edu.ng/work/view/evaluating-the-antimicrobial-activity-of-vernonia-amygdalina-bitter-leaf-extract-on-staphylococcus-aureus-escherichia-coli-and-pseudomonas-aeruginosa-7-2. Accessed 15 Nov. 2024.
IDUME, IDUME. "Evaluating The Antimicrobial Activity Of Vernonia Amygdalina (Bitter Leaf Extract) On Staphylococcus Aureus, Escherichia Coli And Pseudomonas Aeruginosa". Mouau.afribary.org, Mouau.afribary.org, 04 Nov. 2021. Web. 15 Nov. 2024. < https://repository.mouau.edu.ng/work/view/evaluating-the-antimicrobial-activity-of-vernonia-amygdalina-bitter-leaf-extract-on-staphylococcus-aureus-escherichia-coli-and-pseudomonas-aeruginosa-7-2 >.
IDUME, IDUME. "Evaluating The Antimicrobial Activity Of Vernonia Amygdalina (Bitter Leaf Extract) On Staphylococcus Aureus, Escherichia Coli And Pseudomonas Aeruginosa" Mouau.afribary.org (2021). Accessed 15 Nov. 2024. https://repository.mouau.edu.ng/work/view/evaluating-the-antimicrobial-activity-of-vernonia-amygdalina-bitter-leaf-extract-on-staphylococcus-aureus-escherichia-coli-and-pseudomonas-aeruginosa-7-2