Effects Of Ethanolic Root Extract Of Sphenocentrum jollyanum On Some Serum Electrolyte (Na+ ,K+, CI-,HCO3.) In Induced Diabetic Wistar Albino Rat :- Eberechukwu, Jenefa .C.
ABSTRACT
Roots
of Sphenocentrum joUyamtm are used as Anti-diabetic, anti-hyperglycemic and
treatment constipation. The present study was aimed at evaluating the effects
of ethanolic root extract of S.jollyanum on some electrolytes
(Na’,K’,Cl-,11CO3) in diabetic Wistar Albino Rat. Twenty(20) rats were used to
carry out this experiment and was grouped into five of four groups; Group 1
:Normal control(no diabetes and fed with feed and water),Group 2: Low
dose(diabetic and treated with 200mg/kg),Group 3Positive control(diabetic and
treated with glibenclamide), Group 4.’High dose(diabetic and treated with
400mg/kg), Group 5:Negative control(diabetic and not treated).Results: When 200mg/kg
and 400mg/kg of the extract was compared with Group 5,there was a
significant(p<0.05) decrease in DayO and a not significant(p>0.05) dose
dependent decrease in wcek2 and 3.Also there was a significant (p<0.05)
decrease in the serum electrolytes(Na4, K',C1-, HCO3') from the bar chart.
Conclusion: The plant extract was toxic because it contains inhibitory
compounds that decreases the absorption of these electrolytes(NaL KLC1‘, HCO3)
and it also contains antioxidants, antihyperglycemic properties.
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EBERECHUKWU, J (2023). Effects Of Ethanolic Root Extract Of Sphenocentrum jollyanum On Some Serum Electrolyte (Na+ ,K+, CI-,HCO3.) In Induced Diabetic Wistar Albino Rat :- Eberechukwu, Jenefa .C.. Mouau.afribary.org: Retrieved Nov 17, 2024, from https://repository.mouau.edu.ng/work/view/effects-of-ethanolic-root-extract-of-sphenocentrum-jollyanum-on-some-serum-electrolyte-na-k-ci-hco3-in-induced-diabetic-wistar-albino-rat-eberechukwu-jenefa-c-7-2
JENEFA.C, EBERECHUKWU. "Effects Of Ethanolic Root Extract Of Sphenocentrum jollyanum On Some Serum Electrolyte (Na+ ,K+, CI-,HCO3.) In Induced Diabetic Wistar Albino Rat :- Eberechukwu, Jenefa .C." Mouau.afribary.org. Mouau.afribary.org, 17 Oct. 2023, https://repository.mouau.edu.ng/work/view/effects-of-ethanolic-root-extract-of-sphenocentrum-jollyanum-on-some-serum-electrolyte-na-k-ci-hco3-in-induced-diabetic-wistar-albino-rat-eberechukwu-jenefa-c-7-2. Accessed 17 Nov. 2024.
JENEFA.C, EBERECHUKWU. "Effects Of Ethanolic Root Extract Of Sphenocentrum jollyanum On Some Serum Electrolyte (Na+ ,K+, CI-,HCO3.) In Induced Diabetic Wistar Albino Rat :- Eberechukwu, Jenefa .C.". Mouau.afribary.org, Mouau.afribary.org, 17 Oct. 2023. Web. 17 Nov. 2024. < https://repository.mouau.edu.ng/work/view/effects-of-ethanolic-root-extract-of-sphenocentrum-jollyanum-on-some-serum-electrolyte-na-k-ci-hco3-in-induced-diabetic-wistar-albino-rat-eberechukwu-jenefa-c-7-2 >.
JENEFA.C, EBERECHUKWU. "Effects Of Ethanolic Root Extract Of Sphenocentrum jollyanum On Some Serum Electrolyte (Na+ ,K+, CI-,HCO3.) In Induced Diabetic Wistar Albino Rat :- Eberechukwu, Jenefa .C." Mouau.afribary.org (2023). Accessed 17 Nov. 2024. https://repository.mouau.edu.ng/work/view/effects-of-ethanolic-root-extract-of-sphenocentrum-jollyanum-on-some-serum-electrolyte-na-k-ci-hco3-in-induced-diabetic-wistar-albino-rat-eberechukwu-jenefa-c-7-2