Effect Of Aqueous Extract Of Pleurotus Ostreatus Grown On Hci-Treated Palm Oil Bunch On Some Hematological Parameters In Wistar Albino Rats
ABSTRACT
This study investigated the effect of aqueous extract of Pleurotus ostreatus grown on HC1-treated Palm Oil Bunch on some hematological parameters (WBC, RBC, PCV Hb and Platelet) in Wistar Albino Rats. Twenty-four rats weighing 80- 130g were divided into six groups of four rats per group. Group 1 was control group. Group 2, 3, 4, 5 and 6 were treated with the plant extracts at 0.1%, 0.2%, 0.3%, 0.4% and 0.5% HC1 concentrations respectively. Oral administration of aqueous extract of Pleurotus ostreatus lasted for 21 days. At the end of the 21 days, blood samples were collected by ocular puncture for the determination of hematological parameter: WBC, Hb, PCV RBC and platelets after which the rats were sacrificed. The results showed a significant (P<0.05) increase in the WBC in two test groups (0.2% HC1 and 0.3% HCJ) when compared against the control. There was no significant (P>0.05) difference in the level of HB, RBC, PCV and Platelets in five extract groups (0.1 % HC1, 0.2 % HC1, 0.3% HCl, 0.4 % HC1 and 0.5% HC1) when compared against the control. The results suggest that the aqueous extract of Pleurotus ostreatus grown on HC1-treated Palm Oil Bunch has no toxicological effect on the hematological parameters (PCV, Hb, RBC, and Platelets) and therefore is good for consumption. On the other hand, the significant increase in the WBC level shows that the extract has the capacity to increase the immune system levels in man and animals.
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NNAJI, N (2021). Effect Of Aqueous Extract Of Pleurotus Ostreatus Grown On Hci-Treated Palm Oil Bunch On Some Hematological Parameters In Wistar Albino Rats. Mouau.afribary.org: Retrieved Nov 17, 2024, from https://repository.mouau.edu.ng/work/view/effect-of-aqueous-extract-of-pleurotus-ostreatus-grown-on-hci-treated-palm-oil-bunch-on-some-hematological-parameters-in-wistar-albino-rats-7-2
NKIRUKA, NNAJI. "Effect Of Aqueous Extract Of Pleurotus Ostreatus Grown On Hci-Treated Palm Oil Bunch On Some Hematological Parameters In Wistar Albino Rats" Mouau.afribary.org. Mouau.afribary.org, 25 Jun. 2021, https://repository.mouau.edu.ng/work/view/effect-of-aqueous-extract-of-pleurotus-ostreatus-grown-on-hci-treated-palm-oil-bunch-on-some-hematological-parameters-in-wistar-albino-rats-7-2. Accessed 17 Nov. 2024.
NKIRUKA, NNAJI. "Effect Of Aqueous Extract Of Pleurotus Ostreatus Grown On Hci-Treated Palm Oil Bunch On Some Hematological Parameters In Wistar Albino Rats". Mouau.afribary.org, Mouau.afribary.org, 25 Jun. 2021. Web. 17 Nov. 2024. < https://repository.mouau.edu.ng/work/view/effect-of-aqueous-extract-of-pleurotus-ostreatus-grown-on-hci-treated-palm-oil-bunch-on-some-hematological-parameters-in-wistar-albino-rats-7-2 >.
NKIRUKA, NNAJI. "Effect Of Aqueous Extract Of Pleurotus Ostreatus Grown On Hci-Treated Palm Oil Bunch On Some Hematological Parameters In Wistar Albino Rats" Mouau.afribary.org (2021). Accessed 17 Nov. 2024. https://repository.mouau.edu.ng/work/view/effect-of-aqueous-extract-of-pleurotus-ostreatus-grown-on-hci-treated-palm-oil-bunch-on-some-hematological-parameters-in-wistar-albino-rats-7-2