Beta-lactamase production by antibiotic resistant Staphylococcus aureus isolated from wound patients in Federal Medical Centre Umuahia Abia State:- Nwokocha, Chinaza .E.
ABSTRACT
The present
study was undertaken to investigate the /Mactamase production by antibiotic
resistant Staphylococcus aureus isolated from wound samples from patients at
the Federal Medical Center Umuahia, Abia State. A total of 50 wound swabs from
different sites including burns, skin infection and accident wounds were
analysed in this study. The swabs were streaked directly onto mannitol salt
agar plates. A total of 29 (58.0%) ofthe samples analysed harbored Staphylococcus
aureus. Distribution of the S. aureus among the sample types showed that 83.3%
ofthe skin swabs had 5. aureus, 60% from accident wound and 38.9% was from
burns. The results ofthe antibiotic susceptibility profile ofthe S. aureus
isolates showed that 79.3% and 72.4% ofthe isolates were susceptible to
Ciprofloxacin and Ofloxacin respectively while Gentamicin had 62.1%
susceptibility. The isolates showed 100% resistance to Cefuroxime, Cefepime and
had 34.4% susceptibility to Azithromycin. It was also found that 16(55.2%) of the
total isolates tested positive to /Mactamase production whereas 44.8% were
negative. The study concludes that 5. aureus is the constantly isolated pathogen
in wound patients and regular intervention is required for the control of
infection caused by this organism. With high susceptibility of S. aureus
isolates to Levofloxacin and Ciprofloxacin there is therefore, an indication
that these antibiotics can be used for empirical treatment of infections on
patients wounds
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CHINAZA, E (2023). Beta-lactamase production by antibiotic resistant Staphylococcus aureus isolated from wound patients in Federal Medical Centre Umuahia Abia State:- Nwokocha, Chinaza .E.. Mouau.afribary.org: Retrieved Sep 19, 2024, from https://repository.mouau.edu.ng/work/view/beta-lactamase-production-by-antibiotic-resistant-staphylococcus-aureus-isolated-from-wound-patients-in-federal-medical-centre-umuahia-abia-state-nwokocha-chinaza-e-7-2
ELIZABETH, CHINAZA. "Beta-lactamase production by antibiotic resistant Staphylococcus aureus isolated from wound patients in Federal Medical Centre Umuahia Abia State:- Nwokocha, Chinaza .E." Mouau.afribary.org. Mouau.afribary.org, 19 Oct. 2023, https://repository.mouau.edu.ng/work/view/beta-lactamase-production-by-antibiotic-resistant-staphylococcus-aureus-isolated-from-wound-patients-in-federal-medical-centre-umuahia-abia-state-nwokocha-chinaza-e-7-2. Accessed 19 Sep. 2024.
ELIZABETH, CHINAZA. "Beta-lactamase production by antibiotic resistant Staphylococcus aureus isolated from wound patients in Federal Medical Centre Umuahia Abia State:- Nwokocha, Chinaza .E.". Mouau.afribary.org, Mouau.afribary.org, 19 Oct. 2023. Web. 19 Sep. 2024. < https://repository.mouau.edu.ng/work/view/beta-lactamase-production-by-antibiotic-resistant-staphylococcus-aureus-isolated-from-wound-patients-in-federal-medical-centre-umuahia-abia-state-nwokocha-chinaza-e-7-2 >.
ELIZABETH, CHINAZA. "Beta-lactamase production by antibiotic resistant Staphylococcus aureus isolated from wound patients in Federal Medical Centre Umuahia Abia State:- Nwokocha, Chinaza .E." Mouau.afribary.org (2023). Accessed 19 Sep. 2024. https://repository.mouau.edu.ng/work/view/beta-lactamase-production-by-antibiotic-resistant-staphylococcus-aureus-isolated-from-wound-patients-in-federal-medical-centre-umuahia-abia-state-nwokocha-chinaza-e-7-2