ABSTRACT
Antimicrobial
effects of Chromolaena ocorata (commonly called Siam weed), were tested on
Salmonella typhi, Pseudomonas aeruginosa, Staphylococcus aureus and Candida
albi cans. Different solvents such as methanol and chloroform were used for the
leaf extraction. Test organism Pseudomonas aeruginosa and Salmonella typhi were
susceptible to methanol extracts of Chromolaena odorata at concentration of 25,
50 and 100mg/mi with zone of inhibition of 15mm, 19mm and 22mm respectively for
Salmonella l)phi and 29mm, 32mm and 36mm for Pseudomonas aeruginosa, while the
chloroform extract produced similar concentration of 18mm, 20mm and 22mm for
Salmonella typhi and 19mm, 20mm and 21mm for Pseudomonas aeruginosa. The
Minimum Inhibitory Concentration (MIC) of methanol extract against Salmonella
typhi and Pseudomonas aeruginosa were 12.5mg/mi and 3.12mg/mi respectively. The
MIC of chloroform extract against Salmonella typhi and Pseudomonas aeruginosa
were 6.25mg/mi and 6.25mg/mi. For the pathogen Staphylococcus aureus and
Candida albicans, no MIC was carried out because there was no zone of
inhibition seen on the plate with 100% concentration. This justifies the
therapeutic use of Chromolaena odorata. This research work establishes a good
support to the use of these plants in herbal remedies and for the development
of new drugs.
AGHAMOBI, H (2021). Antimicrobial Effects Of The Leaf Extracts Of Cliromolaena Ordorata (Siam Weeds) On Some Human Pathogens . Mouau.afribary.org: Retrieved Nov 16, 2024, from https://repository.mouau.edu.ng/work/view/antimicrobial-effects-of-the-leaf-extracts-of-cliromolaena-ordorata-siam-weeds-on-some-human-pathogens-7-2
HELEN, AGHAMOBI. "Antimicrobial Effects Of The Leaf Extracts Of Cliromolaena Ordorata (Siam Weeds) On Some Human Pathogens " Mouau.afribary.org. Mouau.afribary.org, 02 Aug. 2021, https://repository.mouau.edu.ng/work/view/antimicrobial-effects-of-the-leaf-extracts-of-cliromolaena-ordorata-siam-weeds-on-some-human-pathogens-7-2. Accessed 16 Nov. 2024.
HELEN, AGHAMOBI. "Antimicrobial Effects Of The Leaf Extracts Of Cliromolaena Ordorata (Siam Weeds) On Some Human Pathogens ". Mouau.afribary.org, Mouau.afribary.org, 02 Aug. 2021. Web. 16 Nov. 2024. < https://repository.mouau.edu.ng/work/view/antimicrobial-effects-of-the-leaf-extracts-of-cliromolaena-ordorata-siam-weeds-on-some-human-pathogens-7-2 >.
HELEN, AGHAMOBI. "Antimicrobial Effects Of The Leaf Extracts Of Cliromolaena Ordorata (Siam Weeds) On Some Human Pathogens " Mouau.afribary.org (2021). Accessed 16 Nov. 2024. https://repository.mouau.edu.ng/work/view/antimicrobial-effects-of-the-leaf-extracts-of-cliromolaena-ordorata-siam-weeds-on-some-human-pathogens-7-2