ABSTRACT
The antifungal
activities of Senna alata was investigated
against four species of dermatophytes namely Trichophyton rubrum, Trichophyton mentagrophyte, Trichophyton tonsurans
and Microsporum canis from scrapings of children with Tinea
capitis and tinea corporis using the radial growth method which showed a marked
antiungal effect on the dermatophytes. The Methanolic extract showed
concentration dependent antifungal activity against the dermotophytes. The
radial hyphal growth of Trichophyton
tonsurans was the most inhibited with 6mm growth at 2mg/ml. At 10mg/ml, the
radial hyphal growth was reduced to 1mm, representing 90% reduction in radial
growth. At 10mg/ml, there was a total inhibition of radial growth of M. canis. The water extract showed
higher antifungal activities against dermatophytes, causing inhibition of
radial growth of 4mm against T.
mentagrophyte at 2mg/ml and complete inhibition at 10mg/ml. The results of
this study suggest that senna alata
has antifungal activities against the agents of Tinea capitis and Tinea
corporis.
CHINEKWE, A (2023). Antifungal Effect Of Senna Alata On Tinea Capitis And Tinea Corporis :- Chinekwe, Amarachi . Mouau.afribary.org: Retrieved Nov 24, 2024, from https://repository.mouau.edu.ng/work/view/antifungal-effect-of-senna-alata-on-tinea-capitis-and-tinea-corporis-chinekwe-amarachi-7-2
AMARACHI, CHINEKWE. "Antifungal Effect Of Senna Alata On Tinea Capitis And Tinea Corporis :- Chinekwe, Amarachi " Mouau.afribary.org. Mouau.afribary.org, 19 Oct. 2023, https://repository.mouau.edu.ng/work/view/antifungal-effect-of-senna-alata-on-tinea-capitis-and-tinea-corporis-chinekwe-amarachi-7-2. Accessed 24 Nov. 2024.
AMARACHI, CHINEKWE. "Antifungal Effect Of Senna Alata On Tinea Capitis And Tinea Corporis :- Chinekwe, Amarachi ". Mouau.afribary.org, Mouau.afribary.org, 19 Oct. 2023. Web. 24 Nov. 2024. < https://repository.mouau.edu.ng/work/view/antifungal-effect-of-senna-alata-on-tinea-capitis-and-tinea-corporis-chinekwe-amarachi-7-2 >.
AMARACHI, CHINEKWE. "Antifungal Effect Of Senna Alata On Tinea Capitis And Tinea Corporis :- Chinekwe, Amarachi " Mouau.afribary.org (2023). Accessed 24 Nov. 2024. https://repository.mouau.edu.ng/work/view/antifungal-effect-of-senna-alata-on-tinea-capitis-and-tinea-corporis-chinekwe-amarachi-7-2