Antibiotic Susceptibility Pattern Of Escherichia Coli Isolated From Waste Water In Umuahia
ABSTRACT
The antibiotic susceptibility pattern of
E.coli in waste water from Umuahia Metropolis was investigated. A total of 17
(85%) E.coli were isolated from the waste water samples. All 17 isolates were
subjected to antibiotics susceptibility test using Kirby Bauer disc diffusion
method. A total of 12 antibiotic discs namely; Ceftazidime (30mg), Cefuroxime
(30mg), Gentamicin (10mg), Ciprofloxacin (5mg), Ofloxacin (5mg), Augumentin (30mg),
Nitrofurantoin (300mg), Ampicillin (10mg) Imipenem (10mg), Menopenem (10mg),
Aztreonam (30mg) and Ceftriaxone (30mg) were used. The E.coli isolates showed
highest susceptibility to both Gentamicin and Ofloxacin (41.1%), followed by
Ceftriaxone 76.5%. Also 17 (100%) of the isolates were found to be multi drug
resistant (MDR). The E.coli isolates were screened for ESBLs in accordance to
the CLSI breakpoint and 17(100) were positive. On subjecting the 17CLSI
positive isolates to double disc synergy test (DDST), 12 (70.6%) were confirmed
to be ESBL producers. This result shows that waste waters found in Umuahia
Metropolis could serve as a reservoir for antibiotic resistant E.coli.
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CHIMEMELA, M (2020). Antibiotic Susceptibility Pattern Of Escherichia Coli Isolated From Waste Water In Umuahia. Mouau.afribary.org: Retrieved Sep 20, 2024, from https://repository.mouau.edu.ng/work/view/antibiotic-susceptibility-pattern-of-escherichia-coli-isolated-from-waste-water-in-umuahia
MOUAU/MCB/14/22021, CHIMEMELA. "Antibiotic Susceptibility Pattern Of Escherichia Coli Isolated From Waste Water In Umuahia" Mouau.afribary.org. Mouau.afribary.org, 14 May. 2020, https://repository.mouau.edu.ng/work/view/antibiotic-susceptibility-pattern-of-escherichia-coli-isolated-from-waste-water-in-umuahia. Accessed 20 Sep. 2024.
MOUAU/MCB/14/22021, CHIMEMELA. "Antibiotic Susceptibility Pattern Of Escherichia Coli Isolated From Waste Water In Umuahia". Mouau.afribary.org, Mouau.afribary.org, 14 May. 2020. Web. 20 Sep. 2024. < https://repository.mouau.edu.ng/work/view/antibiotic-susceptibility-pattern-of-escherichia-coli-isolated-from-waste-water-in-umuahia >.
MOUAU/MCB/14/22021, CHIMEMELA. "Antibiotic Susceptibility Pattern Of Escherichia Coli Isolated From Waste Water In Umuahia" Mouau.afribary.org (2020). Accessed 20 Sep. 2024. https://repository.mouau.edu.ng/work/view/antibiotic-susceptibility-pattern-of-escherichia-coli-isolated-from-waste-water-in-umuahia