ABSTRACT

This study was carried out to determine the antibacterial activity of different toothpastes on dental bacterial. Oral samples were collected before early morning brushing with water from students. Five brands of toothpaste namely Close up, Maclean, oral B, Darbur herbal and Coalgate were tested for their antibacterial activity on Staphylococcus aureus, Streptococcus spp, and Escherichia coli using agar disc diffusion method at different concentrations. Biochemical characterization, Minimum inhibitory concentration were also determined. This study proved that triclosan and sodium fluoride containing toothpaste formulations is more effective in the control of oral micro flora compared to non triclosan containing toothpaste. Based on this study, Coalgate toothpaste are potent antibacterial agent in combating carries causing bacteria and should be comfortably used by individual as suitable oral care product for preventing dental infections, followed by oral B, Darbur herbal, Close up, and the least was Maclean toothpaste.