Β-Lactamase Production By Antibiotic Resistant Staphylococcus Aureus Isolated From Wound Patients In Federal Medical Centre Umuahia Abia State, Nigeria
ABSTRACT
The present study was undertaken to investigate the β-lactamase production by antibiotic resistant Staphylococcus aureus isolated from wound samples from patients at the Federal Medical Center Umuahia, Abia State. A total of 50 wound swabs from different sites including burns, skin infection and accident wounds were analysed in this study. The swabs were streaked directly onto mannitol salt agar plates. A total of 29 (58.0%) of the samples analysed harbored Staphylococcus aureus. Distribution of the S. aureus among the sample types showed that 83.3% of the skin swabs had S. aureus, 60% from accident wound and 38.9% was from burns. The results of the antibiotic susceptibility profile of the S. aureus isolates showed that 79.3% and 72.4% of the isolates were susceptible to Ciprofloxacin and Ofloxacin respectively while Gentamicin had 62.1% susceptibility. The isolates showed 100% resistance to Cefuroxime, Cefepime and had 34.4% susceptibility to Azithromycin. It was also found that 16(55.2%) of the total isolates tested positive to β-lactamase production whereas 44.8% were negative. The study concludes that S. aureus is the constantly isolated pathogen in wound patients and regular intervention is required for the control of infection caused by this organism. With high susceptibility of S. aureus isolates to Levofloxacin and Ciprofloxacin there is therefore, an indication that these antibiotics can be used for empirical treatment of infections on patients wounds.
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NWOKOCHA, E (2021). Β-Lactamase Production By Antibiotic Resistant Staphylococcus Aureus Isolated From Wound Patients In Federal Medical Centre Umuahia Abia State, Nigeria. Mouau.afribary.org: Retrieved Nov 16, 2024, from https://repository.mouau.edu.ng/work/view/-lactamase-production-by-antibiotic-resistant-staphylococcus-aureus-isolated-from-wound-patients-in-federal-medical-centre-umuahia-abia-state-nigeria-7-2
ELIZABETH, NWOKOCHA. " Β-Lactamase Production By Antibiotic Resistant Staphylococcus Aureus Isolated From Wound Patients In Federal Medical Centre Umuahia Abia State, Nigeria" Mouau.afribary.org. Mouau.afribary.org, 15 Oct. 2021, https://repository.mouau.edu.ng/work/view/-lactamase-production-by-antibiotic-resistant-staphylococcus-aureus-isolated-from-wound-patients-in-federal-medical-centre-umuahia-abia-state-nigeria-7-2. Accessed 16 Nov. 2024.
ELIZABETH, NWOKOCHA. " Β-Lactamase Production By Antibiotic Resistant Staphylococcus Aureus Isolated From Wound Patients In Federal Medical Centre Umuahia Abia State, Nigeria". Mouau.afribary.org, Mouau.afribary.org, 15 Oct. 2021. Web. 16 Nov. 2024. < https://repository.mouau.edu.ng/work/view/-lactamase-production-by-antibiotic-resistant-staphylococcus-aureus-isolated-from-wound-patients-in-federal-medical-centre-umuahia-abia-state-nigeria-7-2 >.
ELIZABETH, NWOKOCHA. " Β-Lactamase Production By Antibiotic Resistant Staphylococcus Aureus Isolated From Wound Patients In Federal Medical Centre Umuahia Abia State, Nigeria" Mouau.afribary.org (2021). Accessed 16 Nov. 2024. https://repository.mouau.edu.ng/work/view/-lactamase-production-by-antibiotic-resistant-staphylococcus-aureus-isolated-from-wound-patients-in-federal-medical-centre-umuahia-abia-state-nigeria-7-2